Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum

In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NM...

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Detalles Bibliográficos
Autores principales: Wang, Shang-Kwei, Yeh, Tsun-Tai, Duh, Chang-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475276/
https://www.ncbi.nlm.nih.gov/pubmed/23118724
http://dx.doi.org/10.3390/md10092103
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author Wang, Shang-Kwei
Yeh, Tsun-Tai
Duh, Chang-Yih
author_facet Wang, Shang-Kwei
Yeh, Tsun-Tai
Duh, Chang-Yih
author_sort Wang, Shang-Kwei
collection PubMed
description In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NMR spectroscopic analysis and physical data. The anti-HCMV (human cytomegalovirus) activity of 1–3 and their cytotoxicity against selected cancer cell lines were evaluated.
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spelling pubmed-34752762012-11-01 Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum Wang, Shang-Kwei Yeh, Tsun-Tai Duh, Chang-Yih Mar Drugs Article In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NMR spectroscopic analysis and physical data. The anti-HCMV (human cytomegalovirus) activity of 1–3 and their cytotoxicity against selected cancer cell lines were evaluated. MDPI 2012-09-24 /pmc/articles/PMC3475276/ /pubmed/23118724 http://dx.doi.org/10.3390/md10092103 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wang, Shang-Kwei
Yeh, Tsun-Tai
Duh, Chang-Yih
Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
title Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
title_full Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
title_fullStr Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
title_full_unstemmed Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
title_short Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
title_sort briacavatolides d–f, new briaranes from the taiwanese octocoral briareum excavatum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475276/
https://www.ncbi.nlm.nih.gov/pubmed/23118724
http://dx.doi.org/10.3390/md10092103
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AT duhchangyih briacavatolidesdfnewbriaranesfromthetaiwaneseoctocoralbriareumexcavatum

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