Conformations of the apo-, substrate-bound and phosphate-bound ATP-binding domain of the Cu(II) ATPase CopB illustrate coupling of domain movement to the catalytic cycle

Heavy metal P(1B)-type ATPases play a critical role in cell survival by maintaining appropriate intracellular metal concentrations. Archaeoglobus fulgidus CopB is a member of this family that transports Cu(II) from the cytoplasm to the exterior of the cell using ATP as energy source. CopB has a 264...

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Detalles Bibliográficos
Autores principales: Jayakanthan, Samuel, Roberts, Sue A., Weichsel, Andrzej, Argüello, José M., McEvoy, Megan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475447/
https://www.ncbi.nlm.nih.gov/pubmed/22663904
http://dx.doi.org/10.1042/BSR20120048

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