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Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr(−/−) mice fed on a high-fat diet

The propensity of LDLs (low-density lipoproteins) for aggregation and/or oxidation has been linked to their sphingolipid content, specifically the levels of SM (sphingomyelin) and ceramide. To investigate this association in vivo, ldlr (LDL receptor)-null mice (ldlr(−/−)) were fed on a modified (ath...

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Detalles Bibliográficos
Autores principales:	Deevska, Gergana M., Sunkara, Manjula, Morris, Andrew J., Nikolova-Karakashian, Mariana N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2012
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475451/ https://www.ncbi.nlm.nih.gov/pubmed/22712892 http://dx.doi.org/10.1042/BSR20120036

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