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Recovery of Arrested Replication Forks by Homologous Recombination Is Error-Prone

Homologous recombination is a universal mechanism that allows repair of DNA and provides support for DNA replication. Homologous recombination is therefore a major pathway that suppresses non-homology-mediated genome instability. Here, we report that recovery of impeded replication forks by homologo...

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Detalles Bibliográficos
Autores principales: Iraqui, Ismail, Chekkal, Yasmina, Jmari, Nada, Pietrobon, Violena, Fréon, Karine, Costes, Audrey, Lambert, Sarah A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475662/
https://www.ncbi.nlm.nih.gov/pubmed/23093942
http://dx.doi.org/10.1371/journal.pgen.1002976