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First Discovery of Two Polyketide Synthase Genes for Mitorubrinic Acid and Mitorubrinol Yellow Pigment Biosynthesis and Implications in Virulence of Penicillium marneffei

BACKGROUND: The genome of P. marneffei, the most important thermal dimorphic fungus causing respiratory, skin and systemic mycosis in China and Southeast Asia, possesses 23 polyketide synthase (PKS) genes and 2 polyketide synthase nonribosomal peptide synthase hybrid (PKS-NRPS) genes, which is of hi...

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Detalles Bibliográficos
Autores principales:	Woo, Patrick C. Y., Lam, Ching-Wan, Tam, Emily W. T., Leung, Chris K. F., Wong, Samson S. Y., Lau, Susanna K. P., Yuen, Kwok-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475676/ https://www.ncbi.nlm.nih.gov/pubmed/23094121 http://dx.doi.org/10.1371/journal.pntd.0001871

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