Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection

Autophagy is the mechanism by which cytoplasmic components and organelles are degraded by the lysosomal machinery in response to diverse stimuli including nutrient deprivation, intracellular pathogens, and multiple forms of cellular stress. Here, we show that the membrane-associated E3 ligase RNF5 r...

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Detalles Bibliográficos
Autores principales: Kuang, Ersheng, Okumura, Cheryl Y. M., Sheffy-Levin, Sharon, Varsano, Tal, Shu, Vincent Chih-Wen, Qi, Jianfei, Niesman, Ingrid R., Yang, Huei-Jiun, López-Otín, Carlos, Yang, Wei Yuan, Reed, John C., Broday, Limor, Nizet, Victor, Ronai, Ze'ev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475677/
https://www.ncbi.nlm.nih.gov/pubmed/23093945
http://dx.doi.org/10.1371/journal.pgen.1003007

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