Lack of Significant Metabolic Abnormalities in Mice with Liver-Specific Disruption of 11β-Hydroxysteroid Dehydrogenase Type 1

Glucocorticoids (GC) are implicated in the development of metabolic syndrome, and patients with GC excess share many clinical features, such as central obesity and glucose intolerance. In patients with obesity or type 2 diabetes, systemic GC concentrations seem to be invariably normal. Tissue GC con...

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Detalles Bibliográficos
Autores principales: Lavery, Gareth G., Zielinska, Agnieszka E., Gathercole, Laura L., Hughes, Beverly, Semjonous, Nina, Guest, Phillip, Saqib, Khalid, Sherlock, Mark, Reynolds, Gary, Morgan, Stuart A., Tomlinson, Jeremy W., Walker, Elizabeth A., Rabbitt, Elizabeth H., Stewart, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2012
Materias:
Glucocorticoids-CRH-ACTH-Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475725/
https://www.ncbi.nlm.nih.gov/pubmed/22555437
http://dx.doi.org/10.1210/en.2012-1019

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