Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive

Stressors motivate an array of adaptive responses ranging from “fight or flight” to an internal urgency signal facilitating long-term goals(1). However, traumatic or chronic uncontrollable stress promotes the onset of Major Depressive Disorder where acute stressors lose their motivational properties...

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Detalles Bibliográficos
Autores principales: Lemos, Julia C., Wanat, Matthew J., Smith, Jeffery S., Reyes, Beverly A. S., Hollon, Nick G., Van Bockstaele, Elisabeth J., Chavkin, Charles, Phillips, Paul E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475726/
https://www.ncbi.nlm.nih.gov/pubmed/22992525
http://dx.doi.org/10.1038/nature11436

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