Cargando…

Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review

BACKGROUND: Ependymoma has been described typically as an intramedullary tumor derived from ependymal cells. Intradural extramedullary presentation is rarely described and almost always as a unique lesion. Myxopapillary ependymoma is a histological variant that distinguishes from the ordinary type o...

Descripción completa

Detalles Bibliográficos
Autores principales: Landriel, Federico, Ajler, Pablo, Tedesco, Nicolas, Bendersky, Damián, Vecchi, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475877/
https://www.ncbi.nlm.nih.gov/pubmed/23087818
http://dx.doi.org/10.4103/2152-7806.100859
_version_ 1782246995617906688
author Landriel, Federico
Ajler, Pablo
Tedesco, Nicolas
Bendersky, Damián
Vecchi, Eduardo
author_facet Landriel, Federico
Ajler, Pablo
Tedesco, Nicolas
Bendersky, Damián
Vecchi, Eduardo
author_sort Landriel, Federico
collection PubMed
description BACKGROUND: Ependymoma has been described typically as an intramedullary tumor derived from ependymal cells. Intradural extramedullary presentation is rarely described and almost always as a unique lesion. Myxopapillary ependymoma is a histological variant that distinguishes from the ordinary type of ependymoma because of its generally better prognosis. We present two cases of multicentric extramedullary myxopapillary ependymomas. CASE DESCRIPTION: Case 1 was a 30-year-old man with progressive paresthesia and paresis in the lower limbs, urinary sphincter disturbances, gait instability, ataxia, and chronic low back pain with multiple intradural extramedullary lesions at C2-C3, D2-D4-D5, and D12-L1. Case 2 was a 32-year-old man, presented with low back pain and mild paresthesia in the right lower limb. Magnetic resonance imaging (MRI) showed multiple intradural extramedullary lesions with homogeneous enhancement after gadolinium injection at C7, D2, D4, D5, D8, D10, D11, L1, L3, L5, S1, and S2. Complete tumor resection of the approached tumors was archived in both cases. Histological studies confirm myxopapillary ependymomas. Patient's neurologic outcome was good and no residual tumor was present at MRI control at 10 years in case 1 and 12 months in case 2. CONCLUSIONS: We report the first two cases of multicentric extramedullary myxopapillary ependymomas, this etiology must be taken into account in the differential diagnosis of intradural extramedullary tumors.
format Online
Article
Text
id pubmed-3475877
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-34758772012-10-19 Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review Landriel, Federico Ajler, Pablo Tedesco, Nicolas Bendersky, Damián Vecchi, Eduardo Surg Neurol Int Case Report BACKGROUND: Ependymoma has been described typically as an intramedullary tumor derived from ependymal cells. Intradural extramedullary presentation is rarely described and almost always as a unique lesion. Myxopapillary ependymoma is a histological variant that distinguishes from the ordinary type of ependymoma because of its generally better prognosis. We present two cases of multicentric extramedullary myxopapillary ependymomas. CASE DESCRIPTION: Case 1 was a 30-year-old man with progressive paresthesia and paresis in the lower limbs, urinary sphincter disturbances, gait instability, ataxia, and chronic low back pain with multiple intradural extramedullary lesions at C2-C3, D2-D4-D5, and D12-L1. Case 2 was a 32-year-old man, presented with low back pain and mild paresthesia in the right lower limb. Magnetic resonance imaging (MRI) showed multiple intradural extramedullary lesions with homogeneous enhancement after gadolinium injection at C7, D2, D4, D5, D8, D10, D11, L1, L3, L5, S1, and S2. Complete tumor resection of the approached tumors was archived in both cases. Histological studies confirm myxopapillary ependymomas. Patient's neurologic outcome was good and no residual tumor was present at MRI control at 10 years in case 1 and 12 months in case 2. CONCLUSIONS: We report the first two cases of multicentric extramedullary myxopapillary ependymomas, this etiology must be taken into account in the differential diagnosis of intradural extramedullary tumors. Medknow Publications & Media Pvt Ltd 2012-09-13 /pmc/articles/PMC3475877/ /pubmed/23087818 http://dx.doi.org/10.4103/2152-7806.100859 Text en Copyright: © 2012 Landriel F. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Landriel, Federico
Ajler, Pablo
Tedesco, Nicolas
Bendersky, Damián
Vecchi, Eduardo
Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review
title Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review
title_full Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review
title_fullStr Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review
title_full_unstemmed Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review
title_short Multicentric extramedullary myxopapillary ependymomas: Two case reports and literature review
title_sort multicentric extramedullary myxopapillary ependymomas: two case reports and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475877/
https://www.ncbi.nlm.nih.gov/pubmed/23087818
http://dx.doi.org/10.4103/2152-7806.100859
work_keys_str_mv AT landrielfederico multicentricextramedullarymyxopapillaryependymomastwocasereportsandliteraturereview
AT ajlerpablo multicentricextramedullarymyxopapillaryependymomastwocasereportsandliteraturereview
AT tedesconicolas multicentricextramedullarymyxopapillaryependymomastwocasereportsandliteraturereview
AT benderskydamian multicentricextramedullarymyxopapillaryependymomastwocasereportsandliteraturereview
AT vecchieduardo multicentricextramedullarymyxopapillaryependymomastwocasereportsandliteraturereview