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Pure red cell aplasia in a simultaneous pancreas-kidney transplantation patient: inside the erythroblast

A case of pure red cell aplasia in a simultaneous kidney-pancreas transplant recipient on immunosuppressive therapy is reported here. The patient presented with anemia unresponsive to erythropoietin treatment. Bone marrow cytomorphology was highly suggestive of parvovirus pure red cell aplasia, whic...

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Detalles Bibliográficos
Autores principales: Labbadia, Francesca, Salido-Fierréz, Eduardo, Majado-Martinez, Juliana, Cabañas-Perianes, Valentin, Moraleda, Jiménez José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475939/
https://www.ncbi.nlm.nih.gov/pubmed/23087806
http://dx.doi.org/10.4081/hr.2012.e17
Descripción
Sumario:A case of pure red cell aplasia in a simultaneous kidney-pancreas transplant recipient on immunosuppressive therapy is reported here. The patient presented with anemia unresponsive to erythropoietin treatment. Bone marrow cytomorphology was highly suggestive of parvovirus pure red cell aplasia, which was confirmed with serology and polymerase chain reaction positive for parvovirus B19 DNA in peripheral blood. After the administration of intravenous immunoglobulin the anemia improved with a rising number of the reticulocytes.