Overexpression of lung resistance-related protein and P-glycoprotein and response to induction chemotherapy in acute myelogenous leukemia

Lung resistance-related protein (LRP) and P-glycoprotein (P-gp) are associated with multidrug resistance. P-gp overexpression reduces intracellular anticancer drug concentrations and is correlated with low remission rates. However, whether the presence of LRP influences the response to induction che...

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Autores principales: Tsuji, Kazue, Wang, Yan-Hua, Takanashi, Minoko, Odajima, Tsuyoshi, Lee, Gabriel. A., Sugimori, Hiroki, Motoji, Toshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475940/
https://www.ncbi.nlm.nih.gov/pubmed/23087807
http://dx.doi.org/10.4081/hr.2012.e18

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