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Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients

The present study aimed to evaluate heat pain thresholds and evoked potentials following CO(2) laser thermal stimulation (laser-evoked potentials, LEPs), during remote application of capsaicin, in migraine patients vs. non-migraine healthy controls. Twelve outpatients suffering from migraine without...

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Autores principales: de Tommaso, Marina, Difruscolo, Olimpia, Sardaro, Michele, Libro, Giuseppe, Pecoraro, Carla, Serpino, Claudia, Lamberti, Paolo, Livrea, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476143/
https://www.ncbi.nlm.nih.gov/pubmed/17563842
http://dx.doi.org/10.1007/s10194-007-0385-8
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author de Tommaso, Marina
Difruscolo, Olimpia
Sardaro, Michele
Libro, Giuseppe
Pecoraro, Carla
Serpino, Claudia
Lamberti, Paolo
Livrea, Paolo
author_facet de Tommaso, Marina
Difruscolo, Olimpia
Sardaro, Michele
Libro, Giuseppe
Pecoraro, Carla
Serpino, Claudia
Lamberti, Paolo
Livrea, Paolo
author_sort de Tommaso, Marina
collection PubMed
description The present study aimed to evaluate heat pain thresholds and evoked potentials following CO(2) laser thermal stimulation (laser-evoked potentials, LEPs), during remote application of capsaicin, in migraine patients vs. non-migraine healthy controls. Twelve outpatients suffering from migraine without aura were compared with 10 healthy controls. The LEPs were recorded by 6 scalp electrodes, stimulating the dorsum of the right hand and the right supraorbital zone in basal condition, during the application of 3% capsaicin on the dorsum of the left hand and after capsaicin removal. In normal subjects, the laser pain and the N2-P2 vertex complex obtained by the hand and face stimulation were significantly reduced during remote capsaicin application, with respect to pre-and post-capsaicin conditions, while in migraine LEPs and laser pain were not significantly modified during remote painful stimulation. In migraine a defective brainstem inhibiting control may coexist with cognitive factors of focalised attention to facial pain, less sensitive to distraction by a second pain.
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spelling pubmed-34761432012-11-29 Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients de Tommaso, Marina Difruscolo, Olimpia Sardaro, Michele Libro, Giuseppe Pecoraro, Carla Serpino, Claudia Lamberti, Paolo Livrea, Paolo J Headache Pain Original The present study aimed to evaluate heat pain thresholds and evoked potentials following CO(2) laser thermal stimulation (laser-evoked potentials, LEPs), during remote application of capsaicin, in migraine patients vs. non-migraine healthy controls. Twelve outpatients suffering from migraine without aura were compared with 10 healthy controls. The LEPs were recorded by 6 scalp electrodes, stimulating the dorsum of the right hand and the right supraorbital zone in basal condition, during the application of 3% capsaicin on the dorsum of the left hand and after capsaicin removal. In normal subjects, the laser pain and the N2-P2 vertex complex obtained by the hand and face stimulation were significantly reduced during remote capsaicin application, with respect to pre-and post-capsaicin conditions, while in migraine LEPs and laser pain were not significantly modified during remote painful stimulation. In migraine a defective brainstem inhibiting control may coexist with cognitive factors of focalised attention to facial pain, less sensitive to distraction by a second pain. Springer-Verlag 2007-06-11 2007-06 /pmc/articles/PMC3476143/ /pubmed/17563842 http://dx.doi.org/10.1007/s10194-007-0385-8 Text en © Springer-Verlag Italia 2007
spellingShingle Original
de Tommaso, Marina
Difruscolo, Olimpia
Sardaro, Michele
Libro, Giuseppe
Pecoraro, Carla
Serpino, Claudia
Lamberti, Paolo
Livrea, Paolo
Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients
title Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients
title_full Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients
title_fullStr Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients
title_full_unstemmed Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients
title_short Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients
title_sort effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients
topic Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476143/
https://www.ncbi.nlm.nih.gov/pubmed/17563842
http://dx.doi.org/10.1007/s10194-007-0385-8
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