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Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function
BACKGROUND: The Nef protein of HIV facilitates virus replication and disease progression in infected patients. This role as pathogenesis factor depends on several genetically separable Nef functions that are mediated by interactions of highly conserved protein-protein interaction motifs with differe...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476393/ https://www.ncbi.nlm.nih.gov/pubmed/22537596 http://dx.doi.org/10.1186/1742-4690-9-34 |