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Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

BACKGROUND: The Nef protein of HIV facilitates virus replication and disease progression in infected patients. This role as pathogenesis factor depends on several genetically separable Nef functions that are mediated by interactions of highly conserved protein-protein interaction motifs with differe...

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Detalles Bibliográficos
Autores principales: Meuwissen, Pieter J, Stolp, Bettina, Iannucci, Veronica, Vermeire, Jolien, Naessens, Evelien, Saksela, Kalle, Geyer, Matthias, Vanham, Guido, Arien, Kevin K, Fackler, Oliver T, Verhasselt, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476393/
https://www.ncbi.nlm.nih.gov/pubmed/22537596
http://dx.doi.org/10.1186/1742-4690-9-34