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Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: Gene-environmental interaction with alcohol consumption

BACKGROUND: Genetic variants near/within the ALDH2 gene encoding the mitochondrial aldehyde dehydrogenase 2 have been associated with blood pressure and hypertension in several case–control association studies in East Asian populations. METHODS: Three common tag single nucleotide polymorphisms (tagS...

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Detalles Bibliográficos
Autores principales: Chang, Yi-Cheng, Chiu, Yen-Feng, Lee, I-Te, Ho, Low-Tone, Hung, Yi-Jen, Hsiung, Chao A, Quertermous, Thomas, Donlon, Timothy, Lee, Wei-Jei, Lee, Po-Chu, Chen, Che-Hong, Mochly-Rosen, Daria, Chuang, Lee-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476438/
https://www.ncbi.nlm.nih.gov/pubmed/22839215
http://dx.doi.org/10.1186/1471-2261-12-58