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Dual processing streams in chemosensory perception

Higher order sensory processing follows a general subdivision into a ventral and a dorsal stream for visual, auditory, and tactile information. Object identification is processed in temporal structures (ventral stream), whereas object localization leads to activation of parietal structures (dorsal s...

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Autores principales: Frasnelli, Johannes, Lundström, Johan N., Schöpf, Veronika, Negoias, Simona, Hummel, Thomas, Lepore, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476497/
https://www.ncbi.nlm.nih.gov/pubmed/23091456
http://dx.doi.org/10.3389/fnhum.2012.00288
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author Frasnelli, Johannes
Lundström, Johan N.
Schöpf, Veronika
Negoias, Simona
Hummel, Thomas
Lepore, Franco
author_facet Frasnelli, Johannes
Lundström, Johan N.
Schöpf, Veronika
Negoias, Simona
Hummel, Thomas
Lepore, Franco
author_sort Frasnelli, Johannes
collection PubMed
description Higher order sensory processing follows a general subdivision into a ventral and a dorsal stream for visual, auditory, and tactile information. Object identification is processed in temporal structures (ventral stream), whereas object localization leads to activation of parietal structures (dorsal stream). To examine whether the chemical senses demonstrate a similar dissociation, we investigated odor identification and odor localization in 16 healthy young subjects using functional MRI. We used two odors—(1) eucalyptol; (2) a mixture of phenylethanol and carbon dioxide)—which were delivered to only one nostril. During odor identification subjects had to recognize the odor; during odor localization they had to detect the stimulated nostril. We used general linear model (GLM) as a classical method as well as independent component analysis (ICA) in order to investigate a possible neuroanatomical dissociation between both tasks. Both methods showed differences between tasks—confirming a dual processing stream in the chemical senses—but revealed complementary results. Specifically, GLM identified the left intraparietal sulcus and the right superior frontal sulcus to be more activated when subjects were localizing the odorants. For the same task, ICA identified a significant cluster in the left parietal lobe (paracentral lobule) but also in the right hippocampus. While GLM did not find significant activations for odor identification, ICA revealed two clusters (in the left central fissure and the left superior frontal gyrus) for this task. These data demonstrate that higher order chemosensory processing shares the general subdivision into a ventral and a dorsal processing stream with other sensory systems and suggest that this is a global principle, independent of sensory channels.
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spelling pubmed-34764972012-10-22 Dual processing streams in chemosensory perception Frasnelli, Johannes Lundström, Johan N. Schöpf, Veronika Negoias, Simona Hummel, Thomas Lepore, Franco Front Hum Neurosci Neuroscience Higher order sensory processing follows a general subdivision into a ventral and a dorsal stream for visual, auditory, and tactile information. Object identification is processed in temporal structures (ventral stream), whereas object localization leads to activation of parietal structures (dorsal stream). To examine whether the chemical senses demonstrate a similar dissociation, we investigated odor identification and odor localization in 16 healthy young subjects using functional MRI. We used two odors—(1) eucalyptol; (2) a mixture of phenylethanol and carbon dioxide)—which were delivered to only one nostril. During odor identification subjects had to recognize the odor; during odor localization they had to detect the stimulated nostril. We used general linear model (GLM) as a classical method as well as independent component analysis (ICA) in order to investigate a possible neuroanatomical dissociation between both tasks. Both methods showed differences between tasks—confirming a dual processing stream in the chemical senses—but revealed complementary results. Specifically, GLM identified the left intraparietal sulcus and the right superior frontal sulcus to be more activated when subjects were localizing the odorants. For the same task, ICA identified a significant cluster in the left parietal lobe (paracentral lobule) but also in the right hippocampus. While GLM did not find significant activations for odor identification, ICA revealed two clusters (in the left central fissure and the left superior frontal gyrus) for this task. These data demonstrate that higher order chemosensory processing shares the general subdivision into a ventral and a dorsal processing stream with other sensory systems and suggest that this is a global principle, independent of sensory channels. Frontiers Media S.A. 2012-10-19 /pmc/articles/PMC3476497/ /pubmed/23091456 http://dx.doi.org/10.3389/fnhum.2012.00288 Text en Copyright © 2012 Frasnelli, Lundström, Schöpf, Negoias, Hummel and Lepore. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Neuroscience
Frasnelli, Johannes
Lundström, Johan N.
Schöpf, Veronika
Negoias, Simona
Hummel, Thomas
Lepore, Franco
Dual processing streams in chemosensory perception
title Dual processing streams in chemosensory perception
title_full Dual processing streams in chemosensory perception
title_fullStr Dual processing streams in chemosensory perception
title_full_unstemmed Dual processing streams in chemosensory perception
title_short Dual processing streams in chemosensory perception
title_sort dual processing streams in chemosensory perception
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476497/
https://www.ncbi.nlm.nih.gov/pubmed/23091456
http://dx.doi.org/10.3389/fnhum.2012.00288
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