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Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4
CHD4, the core subunit of the Nucleosome Remodelling and Deacetylase (NuRD) complex, is a chromatin remodelling ATPase that, in addition to a helicase domain, harbors tandem plant homeo finger and chromo domains. By using a panel of domain constructs we dissect their roles and demonstrate that DNA b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science B.V
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476528/ https://www.ncbi.nlm.nih.gov/pubmed/22749909 http://dx.doi.org/10.1016/j.febslet.2012.06.017 |