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Pharmacodynamic Effect of Cilostazol Plus Standard Clopidogrel Versus Double-Dose Clopidogrel in Patients With Type 2 Diabetes Undergoing Percutaneous Coronary Intervention

OBJECTIVE: To determine the effect of adding cilostazol (100 mg b.i.d.) to standard-dose clopidogrel (75 mg/d) (TRIPLE) compared with double-dose clopidogrel (150 mg/d) (DOUBLE) and the influence of the cytochrome P450 (CYP2C19*2/*3, CYP3A5*3)and ATP-binding cassette subfamily B1(ABCB1 C3435T) genet...

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Detalles Bibliográficos
Autores principales: Jeong, Young-Hoon, Tantry, Udaya S., Park, Yongwhi, Kwon, Tae Jung, Park, Jeong Rang, Hwang, Seok-Jae, Bliden, Kevin P., Koh, Eun-Ha, Kwak, Choong Hwan, Hwang, Jin-Yong, Kim, Sunjoo, Gurbel, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476883/
https://www.ncbi.nlm.nih.gov/pubmed/22837373
http://dx.doi.org/10.2337/dc11-2351