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Knock-down of methyl CpG-binding protein 2 (MeCP2) causes alterations in cell proliferation and nuclear lamins expression in mammalian cells

BACKGROUND: MeCP2 (CpG-binding protein 2) is a nuclear multifunctional protein involved in several cellular processes, like large-scale chromatin reorganization and architecture, and transcriptional regulation. In recent years, a non-neuronal role for MeCP2 has emerged in cell growth and proliferati...

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Detalles Bibliográficos
Autores principales: Babbio, Federica, Castiglioni, Ilaria, Cassina, Chiara, Gariboldi, Marzia Bruna, Pistore, Christian, Magnani, Elena, Badaracco, Gianfranco, Monti, Elena, Bonapace, Ian Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477090/
https://www.ncbi.nlm.nih.gov/pubmed/22783988
http://dx.doi.org/10.1186/1471-2121-13-19