Cargando…
In Vivo Imaging of Brain Ischemia Using an Oxygen-Dependent Degradative Fusion Protein Probe
Within the ischemic penumbra, blood flow is sufficiently reduced that it results in hypoxia severe enough to arrest physiological function. Nevertheless, it has been shown that cells present within this region can be rescued and resuscitated by restoring perfusion and through other protective therap...
Autores principales: | Fujita, Youshi, Kuchimaru, Takahiro, Kadonosono, Tetsuya, Tanaka, Shotaro, Hase, Yoshiki, Tomimoto, Hidekazu, Hiraoka, Masahiro, Kizaka-Kondoh, Shinae, Ihara, Masafumi, Takahashi, Ryosuke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477118/ https://www.ncbi.nlm.nih.gov/pubmed/23094105 http://dx.doi.org/10.1371/journal.pone.0048051 |
Ejemplares similares
-
In Vivo Imaging of HIF-Active Tumors by an Oxygen-Dependent Degradation Protein Probe with an Interchangeable Labeling System
por: Kuchimaru, Takahiro, et al.
Publicado: (2010) -
A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system
por: Kuchimaru, Takahiro, et al.
Publicado: (2016) -
Hypoxia‐inducible factor‐targeting prodrug TOP3 combined with gemcitabine or TS‐1 improves pancreatic cancer survival in an orthotopic model
por: Hoang, Ngoc Thi Hong, et al.
Publicado: (2016) -
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging
por: Kuchimaru, Takahiro, et al.
Publicado: (2016) -
Bone resorption facilitates osteoblastic bone metastatic colonization by cooperation of insulin-like growth factor and hypoxia
por: Kuchimaru, Takahiro, et al.
Publicado: (2014)