Co-Operative Additive Effects between HLA Alleles in Control of HIV-1

BACKGROUND: HLA class I genotype is a major determinant of the outcome of HIV infection, and the impact of certain alleles on HIV disease outcome is well studied. Recent studies have demonstrated that certain HLA class I alleles that are in linkage disequilibrium, such as HLA-A*74 and HLA-B*57, appe...

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Detalles Bibliográficos
Autores principales: Matthews, Philippa C., Listgarten, Jennifer, Carlson, Jonathan M., Payne, Rebecca, Huang, Kuan-Hsiang Gary, Frater, John, Goedhals, Dominique, Steyn, Dewald, van Vuuren, Cloete, Paioni, Paolo, Jooste, Pieter, Ogwu, Anthony, Shapiro, Roger, Mncube, Zenele, Ndung'u, Thumbi, Walker, Bruce D., Heckerman, David, Goulder, Philip J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477121/
https://www.ncbi.nlm.nih.gov/pubmed/23094091
http://dx.doi.org/10.1371/journal.pone.0047799

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