Sustained Beta-Cell Dysfunction but Normalized Islet Mass in Aged Thrombospondin-1 Deficient Mice

Pancreatic islet endothelial cells have in recent years been shown to support beta-cell mass and function by paracrine interactions. Recently, we identified an islets endothelial-specific glycoprotein, thrombospondin-1 (TSP-1), that showed to be of importance for islet angiogenesis and beta-cell fun...

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Detalles Bibliográficos
Autores principales: Drott, Carl Johan, Olerud, Johan, Emanuelsson, Hanna, Christoffersson, Gustav, Carlsson, Per-Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477147/
https://www.ncbi.nlm.nih.gov/pubmed/23094049
http://dx.doi.org/10.1371/journal.pone.0047451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477147/
https://www.ncbi.nlm.nih.gov/pubmed/23094049
http://dx.doi.org/10.1371/journal.pone.0047451

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