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Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

BACKGROUND & AIMS: GATA4, a zinc finger domain transcription factor, is critical for jejunal identity. Mice with an intestine-specific GATA4 deficiency (GATA4iKO) are resistant to diet-induced obesity and insulin resistance. Although they have decreased intestinal lipid absorption, hepatic de no...

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Detalles Bibliográficos
Autores principales:	Patankar, Jay V., Obrowsky, Sascha, Doddapattar, Prakash, Hoefler, Gerald, Battle, Michele, Levak-Frank, Sanja, Kratky, Dagmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477492/ https://www.ncbi.nlm.nih.gov/pubmed/22750465 http://dx.doi.org/10.1016/j.jhep.2012.06.028

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