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Suppression of Aldosterone Synthesis and Secretion by Ca(2+) Channel Antagonists
Aldosterone, a specific mineralocorticoid receptor (MR) agonist and a key player in the development of hypertension, is synthesized as a final product of renin-angiotensin-aldosterone system. Hypertension can be generally treated by negating the effects of angiotensin II through the use of angiotens...
Autores principales: | Ikeda, Keiichi, Isaka, Tsuyoshi, Fujioka, Kouki, Manome, Yoshinobu, Tojo, Katsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477571/ https://www.ncbi.nlm.nih.gov/pubmed/23097668 http://dx.doi.org/10.1155/2012/519467 |
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