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Influence of macrolide maintenance therapy and bacterial colonisation on exacerbation frequency and progression of COPD (COLUMBUS): Study protocol for a randomised controlled trial
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterised by progressive development of airflow limitation that is poorly reversible. Because of a poor understanding of COPD pathogenesis, treatment is mostly symptomatic and new therapeutic strategies are limited. There is a direct re...
Autores principales: | Uzun, Sevim, Djamin, Remco S, Kluytmans, JanAJW, Van’t Veer, Nils E, Ermens, Anton A M, Pelle, Aline J, Mulder, Paul, van der Eerden, Menno M, Aerts, JoachimGJV |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478173/ https://www.ncbi.nlm.nih.gov/pubmed/22682323 http://dx.doi.org/10.1186/1745-6215-13-82 |
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