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Protective effect of the Japanese traditional medicine juzentaihoto on myelosuppression induced by the anticancer drug TS-1 and identification of a potential biomarker of this effect
BACKGROUND: TS-1 is an oral anticancer drug containing a 5-fluorouracil derivative (Tegafur) that is widely used in Japan for the treatment of cancer, especially gastrointestinal tumors. Frequently, however, TS-1 therapy has to be discontinued because of leukopenia. If it were possible to predict th...
Autores principales: | Ogawa, Kazuo, Omatsu, Tatsushi, Matsumoto, Chinami, Tsuchiya, Naoko, Yamamoto, Masahiro, Naito, Yuji, Yoshikawa, Toshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478231/ https://www.ncbi.nlm.nih.gov/pubmed/22876791 http://dx.doi.org/10.1186/1472-6882-12-118 |
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