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IGF2BP1: A post-transcriptional “driver” of tumor cell migration

The oncofetal RNA-binding protein IGF2BP1 (IGF2 mRNA binding protein 1) controls the cytoplasmic fate of specific target mRNAs including ACTB and CD44. During neural development, IGF2BPs promote neurite protrusion and the migration of neuronal crest cells. In tumor-derived cells, IGF2BP1 enhances th...

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Detalles Bibliográficos
Autores principales:	Stöhr, Nadine, Hüttelmaier, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478252/ https://www.ncbi.nlm.nih.gov/pubmed/22983196 http://dx.doi.org/10.4161/cam.20628

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