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Anti-Cancer Drugs Elicit Re-Expression of UDP-Glucuronosyltransferases in Melanoma Cells

The UDP-glucuronosyltransferase (UGT) family of enzymes plays a vital role in the detoxification of carcinogens as well as clearance of anti-cancer drugs. In humans, 19 UGT family members have been identified and are expressed in a tissue specific manner throughout the body. However, the UGTs have n...

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Detalles Bibliográficos
Autores principales: Dellinger, Ryan W., Matundan, Harry H., Ahmed, Amelia S., Duong, Priscilla H., Meyskens, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478267/
https://www.ncbi.nlm.nih.gov/pubmed/23110092
http://dx.doi.org/10.1371/journal.pone.0047696