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Depressed Levels of Prostaglandin F(2α) in Mice Lacking Akr1b7 Increase Basal Adiposity and Predispose to Diet-Induced Obesity
Negative regulators of white adipose tissue (WAT) expansion are poorly documented in vivo. Prostaglandin F(2α) (PGF(2α)) is a potent antiadipogenic factor in cultured preadipocytes, but evidence for its involvement in physiological context is lacking. We previously reported that Akr1b7, an aldo-keto...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478517/ https://www.ncbi.nlm.nih.gov/pubmed/22851578 http://dx.doi.org/10.2337/db11-1297 |