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Protective Effects of GLP-1 on Glomerular Endothelium and Its Inhibition by PKCβ Activation in Diabetes

To characterize glucagon-like peptide (GLP)-1 signaling and its effect on renal endothelial dysfunction and glomerulopathy. We studied the expression and signaling of GLP-1 receptor (GLP-1R) on glomerular endothelial cells and the novel finding of protein kinase A–dependent phosphorylation of c-Raf...

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Detalles Bibliográficos
Autores principales:	Mima, Akira, Hiraoka-Yamomoto, Junko, Li, Qian, Kitada, Munehiro, Li, Chenzhong, Geraldes, Pedro, Matsumoto, Motonobu, Mizutani, Koji, Park, Kyoungmin, Cahill, Christopher, Nishikawa, Shin-Ichi, Rask-Madsen, Christian, King, George L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478518/ https://www.ncbi.nlm.nih.gov/pubmed/22826029 http://dx.doi.org/10.2337/db11-1824

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