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Toll-like Receptor 4 Deficiency Promotes the Alternative Activation of Adipose Tissue Macrophages

Obesity is characterized by adipose tissue (AT) macrophage (ATM) accumulation, which promotes AT inflammation and dysfunction. Toll-like receptor 4 (TLR4) deficiency attenuates AT inflammation in obesity but does not impede the accumulation of ATMs. The purpose of the current study was to determine...

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Detalles Bibliográficos
Autores principales:	Orr, Jeb S., Puglisi, Michael J., Ellacott, Kate L.J., Lumeng, Carey N., Wasserman, David H., Hasty, Alyssa H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478520/ https://www.ncbi.nlm.nih.gov/pubmed/22751700 http://dx.doi.org/10.2337/db11-1595

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