Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive intramyocellular lipid (IMCL) storage exceeds intracellular needs and induces lipotoxic events, ultimately contributing to the development of insulin resistance. Lipid droplet (LD)–coating proteins may control...

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Detalles Bibliográficos
Autores principales: Bosma, Madeleen, Hesselink, Matthijs K.C., Sparks, Lauren M., Timmers, Silvie, Ferraz, Maria João, Mattijssen, Frits, van Beurden, Denis, Schaart, Gert, de Baets, Marc H., Verheyen, Fons K., Kersten, Sander, Schrauwen, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478528/
https://www.ncbi.nlm.nih.gov/pubmed/22807032
http://dx.doi.org/10.2337/db11-1402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478528/
https://www.ncbi.nlm.nih.gov/pubmed/22807032
http://dx.doi.org/10.2337/db11-1402

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