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Alterations in Lipid Signaling Underlie Lipodystrophy Secondary to AGPAT2 Mutations

Congenital generalized lipodystrophy (CGL), secondary to AGPAT2 mutation is characterized by the absence of adipocytes and development of severe insulin resistance. In the current study, we investigated the adipogenic defect associated with AGPAT2 mutations. Adipogenesis was studied in muscle-derive...

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Detalles Bibliográficos
Autores principales:	Subauste, Angela R., Das, Arun K., Li, Xiangquan, Elliot, Brandon, Evans, Charles, El Azzouny, Mahmoud, Treutelaar, Mary, Oral, Elif, Leff, Todd, Burant, Charles F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478532/ https://www.ncbi.nlm.nih.gov/pubmed/22872237 http://dx.doi.org/10.2337/db12-0004

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