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Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells

Chemotherapy is a mainstay of cancer treatment. Due to increased drug resistance and the severe side effects of currently used therapeutics, new candidate compounds are required for improvement of therapy success. Shikonin, a natural naphthoquinone, was used in traditional Chinese medicine for the t...

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Detalles Bibliográficos
Autores principales: Wiench, Benjamin, Eichhorn, Tolga, Paulsen, Malte, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478753/
https://www.ncbi.nlm.nih.gov/pubmed/23118796
http://dx.doi.org/10.1155/2012/726025