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Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells

Chemotherapy is a mainstay of cancer treatment. Due to increased drug resistance and the severe side effects of currently used therapeutics, new candidate compounds are required for improvement of therapy success. Shikonin, a natural naphthoquinone, was used in traditional Chinese medicine for the t...

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Detalles Bibliográficos
Autores principales:	Wiench, Benjamin, Eichhorn, Tolga, Paulsen, Malte, Efferth, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478753/ https://www.ncbi.nlm.nih.gov/pubmed/23118796 http://dx.doi.org/10.1155/2012/726025

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