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Inhibition of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension
Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by the progressive narrowing and occlusion of small pulmonary arteries. Current therapies fail to fully reverse this vascular remodeling. Identifying key pathways in disease pathogenesis is therefore required for the d...
Autores principales: | Hameed, Abdul G., Arnold, Nadine D., Chamberlain, Janet, Pickworth, Josephine A., Paiva, Claudia, Dawson, Sarah, Cross, Simon, Long, Lu, Zhao, Lan, Morrell, Nicholas W., Crossman, David C., Newman, Christopher M.H., Kiely, David G., Francis, Sheila E., Lawrie, Allan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478928/ https://www.ncbi.nlm.nih.gov/pubmed/23071256 http://dx.doi.org/10.1084/jem.20112716 |
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