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Neuropilin 1 deficiency on CD4(+)Foxp3(+) regulatory T cells impairs mouse melanoma growth
Infiltration of Foxp3(+) regulatory T (T reg) cells is considered to be a critical step during tumor development and progression. T reg cells supposedly suppress locally an effective anti-tumor immune response within tumor tissues, although the precise mechanism by which T reg cells infiltrate the t...
Autores principales: | Hansen, Wiebke, Hutzler, Marina, Abel, Simone, Alter, Christina, Stockmann, Christian, Kliche, Stefanie, Albert, Juliane, Sparwasser, Tim, Sakaguchi, Shimon, Westendorf, Astrid M., Schadendorf, Dirk, Buer, Jan, Helfrich, Iris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478934/ https://www.ncbi.nlm.nih.gov/pubmed/23045606 http://dx.doi.org/10.1084/jem.20111497 |
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