Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis

Transforming growth factor-β1 (TGF-β1) is a fundamental regulator of immune cell development and function. In this study, we investigated the effects of TGF-β1 on the differentiation of human Langerhans cells (LCs) and identified Axl as a key TGF-β1 effector. Axl belongs to the TAM (Tyro3, Axl, and...

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Detalles Bibliográficos
Autores principales: Bauer, Thomas, Zagórska, Anna, Jurkin, Jennifer, Yasmin, Nighat, Köffel, René, Richter, Susanne, Gesslbauer, Bernhard, Lemke, Greg, Strobl, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478937/
https://www.ncbi.nlm.nih.gov/pubmed/23071254
http://dx.doi.org/10.1084/jem.20120493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478937/
https://www.ncbi.nlm.nih.gov/pubmed/23071254
http://dx.doi.org/10.1084/jem.20120493

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