Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

Innate immune detection of nucleic acids is important for initiation of antiviral responses. Detection of intracellular DNA activates STING-dependent type I interferons (IFNs) and the ASC-dependent inflammasome. Certain members of the AIM2-like receptor (ALR) gene family contribute to each of these...

Descripción completa

Detalles Bibliográficos
Autores principales: Brunette, Rebecca L., Young, Janet M., Whitley, Deborah G., Brodsky, Igor E., Malik, Harmit S., Stetson, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478938/
https://www.ncbi.nlm.nih.gov/pubmed/23045604
http://dx.doi.org/10.1084/jem.20121960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478938/
https://www.ncbi.nlm.nih.gov/pubmed/23045604
http://dx.doi.org/10.1084/jem.20121960

Ejemplares similares