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A framework for assessing the risk of resistance for anti-malarials in development

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Resistance is a constant challenge for anti-infective drug development. Since they kill sensitive organisms, anti-infective agents are bound to exert an evolutionary pressure toward the emergence and spread of resistance mechanisms, if such resistance can arise by stochastic mutation events. New cla...

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Detalles Bibliográficos
Autores principales:	Ding, Xavier C, Ubben, David, Wells, Timothy NC
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478971/ https://www.ncbi.nlm.nih.gov/pubmed/22913649 http://dx.doi.org/10.1186/1475-2875-11-292

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