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A framework for assessing the risk of resistance for anti-malarials in development

Resistance is a constant challenge for anti-infective drug development. Since they kill sensitive organisms, anti-infective agents are bound to exert an evolutionary pressure toward the emergence and spread of resistance mechanisms, if such resistance can arise by stochastic mutation events. New cla...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Ding, Xavier C, Ubben, David, Wells, Timothy NC
स्वरूप: Online लेख मूलपाठ
भाषा:English
प्रकाशित: BioMed Central 2012
विषय:
ऑनलाइन पहुंच:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478971/
https://www.ncbi.nlm.nih.gov/pubmed/22913649
http://dx.doi.org/10.1186/1475-2875-11-292