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A framework for assessing the risk of resistance for anti-malarials in development
Resistance is a constant challenge for anti-infective drug development. Since they kill sensitive organisms, anti-infective agents are bound to exert an evolutionary pressure toward the emergence and spread of resistance mechanisms, if such resistance can arise by stochastic mutation events. New cla...
| Автори: | , , |
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| Формат: | Online Стаття Текст |
| Мова: | English |
| Опубліковано: |
BioMed Central
2012
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| Предмети: | |
| Онлайн доступ: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478971/ https://www.ncbi.nlm.nih.gov/pubmed/22913649 http://dx.doi.org/10.1186/1475-2875-11-292 |