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Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex

BACKGROUND: Fragile X syndrome is caused by lack of fragile X mental retardation protein (FMRP) due to silencing of the FMR1 gene. The metabotropic glutamate receptors (mGluRs) in the central nervous system contribute to higher brain functions including learning/memory, mental disorders and persiste...

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Detalles Bibliográficos
Autores principales: Wang, Hansen, Morishita, Yoshikazu, Miura, Daiki, Naranjo, Jose R, Kida, Satoshi, Zhuo, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478997/
https://www.ncbi.nlm.nih.gov/pubmed/22867433
http://dx.doi.org/10.1186/1756-6606-5-27