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Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex
BACKGROUND: Fragile X syndrome is caused by lack of fragile X mental retardation protein (FMRP) due to silencing of the FMR1 gene. The metabotropic glutamate receptors (mGluRs) in the central nervous system contribute to higher brain functions including learning/memory, mental disorders and persiste...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478997/ https://www.ncbi.nlm.nih.gov/pubmed/22867433 http://dx.doi.org/10.1186/1756-6606-5-27 |