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First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients
BACKGROUND: DepoVax(TM) is a novel non-emulsion depot-forming vaccine platform with the capacity to significantly enhance the immunogenicity of peptide cancer antigens. Naturally processed HLA-A2 restricted peptides presented by breast, ovarian and prostate cancer cells were used as antigens to crea...
Autores principales: | Berinstein, Neil L, Karkada, Mohan, Morse, Michael A, Nemunaitis, John J, Chatta, Gurkamal, Kaufman, Howard, Odunsi, Kunle, Nigam, Rita, Sammatur, Leeladhar, MacDonald, Lisa D, Weir, Genevieve M, Stanford, Marianne M, Mansour, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479010/ https://www.ncbi.nlm.nih.gov/pubmed/22862954 http://dx.doi.org/10.1186/1479-5876-10-156 |
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