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Enhanced efficacy and specificity of epithelial ovarian carcinogenesis by embedding a DMBA-coated cloth strip in the ovary of rat

BACKGROUND: Ovarian cancer is predominant of epithelial cell origin and often present at an advanced stage with poor prognosis. Most animal models of ovarian carcinoma yield thecal/granulose cell tumors, rather than adenocarcinomas. The best reported induction rate of adenocarcinoma in rats is 10-45...

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Detalles Bibliográficos
Autores principales: Huang, Yiping, Jiang, Wei, Wang, Yisheng, Zheng, Yufang, Cong, Qing, Xu, Congjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479048/
https://www.ncbi.nlm.nih.gov/pubmed/22943261
http://dx.doi.org/10.1186/1757-2215-5-21