Cargando…

The Molecular Basis for Recognition of CD1d/α-Galactosylceramide by a Human Non-Vα24 T Cell Receptor

CD1d-mediated presentation of glycolipid antigens to T cells is capable of initiating powerful immune responses that can have a beneficial impact on many diseases. Molecular analyses have recently detailed the lipid antigen recognition strategies utilized by the invariant Vα24-Jα18 TCR rearrangement...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Sagaseta, Jacinto, Kung, Jennifer E., Savage, Paul B., Gumperz, Jenny, Adams, Erin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479090/
https://www.ncbi.nlm.nih.gov/pubmed/23109910
http://dx.doi.org/10.1371/journal.pbio.1001412