GCN2 Has Inhibitory Effect on Human Immunodeficiency Virus-1 Protein Synthesis and Is Cleaved upon Viral Infection

The reversible phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 (eIF2alpha) is a well-characterized mechanism of translational control in response to a wide variety of cellular stresses, including viral infection. Beside PKR, the eIF2alpha kinase GCN2 participates i...

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Detalles Bibliográficos
Autores principales: del Pino, Javier, Jiménez, José Luis, Ventoso, Iván, Castelló, Alfredo, Muñoz-Fernández, Ma. Ángeles, de Haro, César, Berlanga, Juan José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479103/
https://www.ncbi.nlm.nih.gov/pubmed/23110064
http://dx.doi.org/10.1371/journal.pone.0047272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479103/
https://www.ncbi.nlm.nih.gov/pubmed/23110064
http://dx.doi.org/10.1371/journal.pone.0047272

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