K-134, a Phosphodiesterase 3 Inhibitor, Prevents Brain Damage by Inhibiting Thrombus Formation in a Rat Cerebral Infarction Model

BACKGROUND: K-134 is a more potent antiplatelet drug with a selective inhibitory effect on phosphodiesterase 3 (PDE3) compared with its analogue, cilostazol. OBJECTIVES: This study was performed to compare the ameliorating effects of K-134 and cilostazol on brain damage in an experimental photothrom...

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Detalles Bibliográficos
Autores principales: Yoshida, Hideo, Ashikawa, Yuka, Itoh, Shinsuke, Nakagawa, Takashi, Asanuma, Akimune, Tanabe, Sohei, Inoue, Yoshihiro, Hidaka, Hiroyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479105/
https://www.ncbi.nlm.nih.gov/pubmed/23110051
http://dx.doi.org/10.1371/journal.pone.0046432

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