In Situ Mass Spectrometry Imaging and Ex Vivo Characterization of Renal Crystalline Deposits Induced in Multiple Preclinical Drug Toxicology Studies

Drug toxicity observed in animal studies during drug development accounts for the discontinuation of many drug candidates, with the kidney being a major site of tissue damage. Extensive investigations are often required to reveal the mechanisms underlying such toxicological events and in the case of...

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Detalles Bibliográficos
Autores principales: Nilsson, Anna, Forngren, Benita, Bjurström, Sivert, Goodwin, Richard J. A., Basmaci, Elisa, Gustafsson, Ingela, Annas, Anita, Hellgren, Dennis, Svanhagen, Alexander, Andrén, Per E., Lindberg, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479109/
https://www.ncbi.nlm.nih.gov/pubmed/23110069
http://dx.doi.org/10.1371/journal.pone.0047353

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