Inhibition of Cell Division Induced by External Guide Sequences (EGS Technology) Targeting ftsZ

EGS (external guide sequence) technology is a promising approach to designing new antibiotics. EGSs are short antisense oligoribonucleotides that induce RNase P-mediated cleavage of a target RNA by forming a precursor tRNA-like complex. The ftsZ mRNA secondary structure was modeled and EGSs compleme...

Descripción completa

Detalles Bibliográficos
Autores principales: Sala, Carol Davies, Soler-Bistué, Alfonso J. C., Korprapun, Leeann, Zorreguieta, Angeles, Tolmasky, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479136/
https://www.ncbi.nlm.nih.gov/pubmed/23110089
http://dx.doi.org/10.1371/journal.pone.0047690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479136/
https://www.ncbi.nlm.nih.gov/pubmed/23110089
http://dx.doi.org/10.1371/journal.pone.0047690

Ejemplares similares