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Inhibition of Cell Division Induced by External Guide Sequences (EGS Technology) Targeting ftsZ
EGS (external guide sequence) technology is a promising approach to designing new antibiotics. EGSs are short antisense oligoribonucleotides that induce RNase P-mediated cleavage of a target RNA by forming a precursor tRNA-like complex. The ftsZ mRNA secondary structure was modeled and EGSs compleme...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479136/ https://www.ncbi.nlm.nih.gov/pubmed/23110089 http://dx.doi.org/10.1371/journal.pone.0047690 |